Profluent

Biotechnology · Emeryville, CA · Founded 2022 · Privately Held (backing)

Developer of artificial intelligence-driven models designed to create and validate novel proteins for biomedicine. Profluent is based in Emeryville, CA and was founded in 2022. It was valued at $525 million at its early-stage round in Nov 2025, the last priced event on record. It has raised $150 million across 2 recorded rounds; the latest was a $106 million Series B in Nov 2025.

PMV mark · valuation
$525.0M
Oct 2026
Priced at
its early-stage round
Nov 2025
Total raised
$150.0M
Last round
Early Stage VC (Series B)
Nov 2025

Who backs Profluent?

10 investors
InvestorType
Insight Partners (New York)PE / buyout
Spark CapitalVenture capital
Jeff DeanOther
Altimeter Capital ManagementVenture capital
AIX VenturesVenture capital
Bezos ExpeditionsFamily office
Phoenix Venture PartnersVenture capital
Air Street Capital—
Convergent Ventures (San Francisco)—
QB3—
The directory is free. Investor activity — the working column — is Pro.Unlock prospecting columns

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Profluent investors

10 investors are on record for Profluent, including Insight Partners (New York), Spark Capital, Jeff Dean and Altimeter Capital Management. By type, the record holds 4 venture capital firms, 1 family office and 1 private equity firm. The Series B in Nov 2025 drew 4 investors.

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