Biotechnology · Emeryville, CA · Founded 2022 · Privately Held (backing)
Developer of artificial intelligence-driven models designed to create and validate novel proteins for biomedicine. Profluent is based in Emeryville, CA and was founded in 2022. It was valued at $525 million at its early-stage round in Nov 2025, the last priced event on record. It has raised $150 million across 2 recorded rounds; the latest was a $106 million Series B in Nov 2025.
PMV mark · valuation
$525.0M
Oct 2026
Priced at
its early-stage round
Nov 2025
Total raised
$150.0M
Last round
Early Stage VC (Series B)
Nov 2025
Cap table — not yet on record
Profluent's share-class structure hasn't surfaced in our sources yet. Cap tables are assembled from certificates of incorporation, round filings, and disclosures as they land.
Pro members can request priority coverage with a 48-hour turnaround.
Free account
More of Profluent with a free account
·Watch Profluent: the Monday email on marks, rounds and moves