Protego Biopharma

San Diego, CA · Founded 2011 · Privately Held (backing)

Developer of a small molecule therapeutics platform designed to reprogram protein folding for the treatment of various systemic amyloid diseases and protein misfolding diseases. Protego Biopharma is based in San Diego, CA and was founded in 2011. Its last reported valuation was $217 million in Mar 2025. It has raised $182 million across 3 recorded rounds; the latest was a $32.9 million early-stage round in Oct 2025.

Last reported valuation
$216.5M
Oct 2026
Priced at
—
Total raised
$182.1M
Last round
Early Stage VC
Oct 2025
What is Protego Biopharma worth?
$216.5Mlast reported valuation · Oct 2026

Protego Biopharma's last reported valuation, Mar 2025. Nothing priced has surfaced since.

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Valuation timeline

0 priced rounds · 32 daily marks since · Sep 2026 – Oct 2026
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Protego Biopharma funding history

3 rounds
DateRoundRaisedPost-money
Oct 2025Early Stage VC$32.9M▮
Oct 2021Later Stage VC$51.0M▮
Dec 2019Seed Round$1.0M▮
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Protego Biopharma valuation

Protego Biopharma's last reported valuation was $217 million in Mar 2025. No priced round, secondary trade or fund mark has surfaced since.

How much has Protego Biopharma raised?

Protego Biopharma has raised $182 million in total; 3 of its rounds are on record, from 2019 on. The largest on record was a $51 million later-stage round in Oct 2021; the most recent was a $32.9 million early-stage round in Oct 2025.

Protego Biopharma has filed 3 Form Ds with the SEC since 2019, most recently in Dec 2025 ($32.9 million sold to 18 investors).

How Protego Biopharma's valuation is determined

Private company valuations aren’t quoted on an exchange — they’re established in moments: a priced funding round sets a post-money valuation, secondary trades print at a price per share, and SEC-registered funds holding the stock report fair-value marks in their N-PORT filings.

For Protego Biopharma, the most current credible signal sets the number and the older ones confirm it: a live secondary-market price first, then three or more recent prints, then institutional fund marks, and otherwise the last priced round, which never decays. The valuation is the last round’s post-money moved by the price change since that round, so no share count is assumed. Today it is set by last reported valuation. Question about this number? Full methodology →

Frequently asked about Protego Biopharma

What is Protego Biopharma worth?
Protego Biopharma is valued at $216.5M as of Oct 2026. Protego Biopharma's last reported valuation, Mar 2025. Nothing priced has surfaced since.
How much has Protego Biopharma raised?
Protego Biopharma has raised $182.1M in total funding across 3 recorded rounds.
When did Protego Biopharma last raise?
Protego Biopharma last raised in Oct 2025 (Early Stage VC), raising $32.9M.