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Upstream Biotechnology

Durham, NC · Founded 2017 · Privately Held (backing)

Developer of disease-resistant crops intended to eliminate pesticide use. Upstream Biotechnology is based in Durham, NC and was founded in 2017. It is valued at about $1.4 million as of Oct 2026, set by institutional fund marks. It has raised $830,000 across 1 recorded round; the latest was a $625,000 seed round in Aug 2025.

PMV mark · valuation
$1.4M
Oct 2026
Priced at
its seed round
Sep 2025
Total raised
$830K
Last round
Seed Round
Aug 2025

Upstream Biotechnology key facts

as of Oct 2026
  • Developer of disease-resistant crops intended to eliminate pesticide use.
  • Upstream Biotechnology is valued at approximately $1.4M as of Oct 2026, per PrivateMarketView’s mark.
  • It has raised $830K across 1 recorded rounds; the latest was Seed Round ($625K) in Aug 2025.
  • Notable investors include US National Science Foundation, SVG Ventures|THRIVE, Ag Ventures Alliance, AgLaunch, National Science Foundation Innovation Corps Program.
  • 4 institutional filers report fund marks on Upstream Biotechnology across 44 filings.
  • Upstream Biotechnology has filed 1 Form D with the SEC, most recently Sep 2025 ($625K sold to 3 investors).
  • Status: Privately Held (backing).
PrivateMarketView mark
LOW confidence
$1.4M

Institutions disagree (3 filers, 51% apart) — shown at its seed round, Sep 2025 ($1.4M post-money).

set by institutional fund marksas of Oct 2026question about this number?
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Institutional fund marks on Upstream Biotechnology

4 filers · latest Jul 2026

4 SEC-registered funds reported 44 fair-value marks on Upstream Biotechnology between Apr 2025 and Jul 2026. Filer-level marks and implied $/share are available to Pro members.

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Upstream Biotechnology funding rounds

1 rounds
Aug 2025Seed Round$625KSEC filing▮
Full funding history →

Upstream Biotechnology valuation

Upstream Biotechnology is valued at approximately $1.4 million as of Oct 2026. The figure is set by institutional fund marks. The reference point is its seed round in Sep 2025, at a $1.4 million post-money valuation.

Recent activity

In the last 90 days, Upstream Biotechnology's record added 5 institutional fund marks (latest period Jul 2026).

How much has Upstream Biotechnology raised?

Upstream Biotechnology has raised $830,000 in total; 1 of its rounds is on record. The largest on record was a $625,000 seed round in Aug 2025.

Upstream Biotechnology has filed 1 Form D with the SEC, most recently in Sep 2025 ($625,000 sold to 3 investors).

Institutional holders and vehicles

4 SEC-registered funds reported 44 fair-value marks on Upstream Biotechnology between Apr 2025 and Jul 2026, in their N-PORT filings. Filer-level marks and implied per-share values are available to Pro members.

Upstream Biotechnology investors

5 investors are on record for Upstream Biotechnology, including US National Science Foundation, SVG Ventures|THRIVE, Ag Ventures Alliance and AgLaunch. The seed round in Aug 2025 drew 3 investors.

About Upstream Biotechnology

Developer of disease-resistant crops intended to eliminate pesticide use. The company uses patented technology to alter upstream DNA sequences to turn on a defensive gene while also using newly discovered sequence elements called upstream open reading frames, enabling farmers to control pesticide use, reduce production costs, increase crop yield and help meet the demands of this new agricultural landscape.

Sector
Materials and Resources
HQ
Durham, NC, United States
Founded
2017
Employees
7
Ownership
Privately Held (backing)

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