Trailhead Biosystems

Beachwood, OH · Founded 2015 · Privately Held (backing)

Developer of iPSC-derived research cell products and differentiation technologies designed to enable consistent and scalable human cell models. Trailhead Biosystems is based in Beachwood, OH and was founded in 2015. Its last reported valuation was $38.6 million in Nov 2023. It has raised $61.6 million across 4 recorded rounds; the latest was a $20 million early-stage round in Jun 2024.

Last reported valuation
$38.6M
Oct 2026
Priced at
—
Total raised
$61.6M
Last round
Early Stage VC
Jun 2024

Trailhead Biosystems key facts

as of Oct 2026
  • Developer of iPSC-derived research cell products and differentiation technologies designed to enable consistent and scalable human cell models.
  • Trailhead Biosystems is valued at approximately $38.6M as of Oct 2026 (last reported valuation).
  • It has raised $61.6M across 4 recorded rounds; the latest was Early Stage VC ($20.0M) in Jun 2024.
  • Notable investors include Ohio Department of Development, MAK Capital, Advanced Regenerative Manufacturing Institute, Global Cardiovascular Innovation Center, Innovation Fund America — 6 tracked in total.
  • Trailhead Biosystems has filed 7 Form Ds with the SEC since 2020, most recently May 2025 ($20.0M sold to 2 investors).
  • Status: Privately Held (backing).
Last reported valuation
LOW confidence
$38.6M

Trailhead Biosystems's last reported valuation, Nov 2023. Nothing priced has surfaced since.

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Trailhead Biosystems funding rounds

4 rounds
Jun 2024Early Stage VC$20.0MSEC filing▮
Nov 2023Seed Round$3.0MSEC filing▮
Sep 2022Early Stage VC$10.0MSEC filing▮
Oct 2020Early Stage VC$8.6MSEC filing▮

Trailhead Biosystems valuation

Trailhead Biosystems's last reported valuation was $38.6 million in Nov 2023. No priced round, secondary trade or fund mark has surfaced since.

How much has Trailhead Biosystems raised?

Trailhead Biosystems has raised $61.6 million across 4 recorded rounds since 2020. The largest was a $10 million early-stage round in Sep 2022; the most recent was a $20 million early-stage round in Jun 2024.

Trailhead Biosystems has filed 7 Form Ds with the SEC since 2020, most recently in May 2025 ($20 million sold to 2 investors).

Trailhead Biosystems investors

6 investors are on record for Trailhead Biosystems, including Ohio Department of Development, MAK Capital, Advanced Regenerative Manufacturing Institute and Global Cardiovascular Innovation Center. The early-stage round in Jun 2024 drew 4 investors.

About Trailhead Biosystems

Developer of iPSC-derived research cell products and differentiation technologies designed to enable consistent and scalable human cell models. The company offers ready-to-use cell products, custom differentiation services, and a high-dimensional design-of-experiments platform integrating computational modeling, automation, and large-scale data generation, enabling researchers and drug developers to achieve reproducible, high-purity cell differentiation and accelerate disease modeling and preclinical research.

Sector
Healthcare
HQ
Beachwood, OH, United States
Founded
2015
Employees
49
Ownership
Privately Held (backing)

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