Syntis Bio

Boston, MA · Founded 2022 · Privately Held (backing)

Developer of late-stage preclinical drugs designed for oral therapy for obesity, diabetes, and rare diseases. Syntis Bio is based in Boston, MA and was founded in 2022. It was valued at $67 million at its early-stage round in Jun 2025, the last priced event on record. It has raised $48.4 million across 3 recorded rounds; the latest was a $25 million early-stage round in Jun 2025.

PMV mark · valuation
$67.0M
Oct 2026
Priced at
its early-stage round
Jun 2025
Total raised
$48.4M
Last round
Early Stage VC
Jun 2025

Syntis Bio key facts

as of Oct 2026
  • Developer of late-stage preclinical drugs designed for oral therapy for obesity, diabetes, and rare diseases.
  • Syntis Bio is valued at approximately $67.0M as of Oct 2026, set at its early-stage round, Jun 2025; nothing has traded since, per PrivateMarketView’s mark.
  • It has raised $48.4M across 3 recorded rounds; the latest was Early Stage VC ($25.0M) in Jun 2025.
  • Notable investors include National Institutes of Health, Sky9 Capital, Safar Partners, Woori Venture Partners, BOLD Capital Partners — 12 tracked in total.
  • Syntis Bio has filed 4 Form Ds with the SEC since 2022, most recently Jul 2025 ($25.0M sold to 12 investors).
  • Status: Privately Held (backing).
PrivateMarketView mark
LOW confidence
$67.0M

Valued at $67.0M at its early-stage round, Jun 2025. Nothing has traded since.

set by its last priced roundas of Oct 2026question about this number?
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Syntis Bio funding rounds

3 rounds
Jun 2025Early Stage VC$25.0MSEC filing▮
Dec 2024Early Stage VC$6.3MSEC filing▮
Aug 2022Early Stage VC$15.4MSEC filing▮

Syntis Bio valuation

Syntis Bio was valued at $67 million at its early-stage round in Jun 2025. That is the last priced event on record: no secondary trade or institutional fund mark has moved the figure since.

How much has Syntis Bio raised?

Syntis Bio has raised $48.4 million across 3 recorded rounds since 2022. The largest was a $6.3 million early-stage round in Dec 2024; the most recent was a $25 million early-stage round in Jun 2025.

Syntis Bio has filed 4 Form Ds with the SEC since 2022, most recently in Jul 2025 ($25 million sold to 12 investors).

Syntis Bio investors

12 investors are on record for Syntis Bio, including National Institutes of Health, Sky9 Capital, Safar Partners and Woori Venture Partners. The early-stage round in Jun 2025 drew 12 investors.

About Syntis Bio

Developer of late-stage preclinical drugs designed for oral therapy for obesity, diabetes, and rare diseases. The company's drug uses formulations for oral therapies that target specific tissues to leverage the small intestine's biology for metabolic and rare disease treatments through a daily nutrient-blocking pill using transient polymer coatings and gut-stable enzyme therapies, enabling researchers to treat patients within a broader disease category and with an effective options that mimic surgical benefits and reduce dietary restrictions.

Sector
Healthcare
HQ
Boston, MA, United States
Founded
2022
Employees
17
Ownership
Privately Held (backing)

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