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Plexium

Drug Discovery · San Diego, CA · Founded 2017 · Privately Held (backing)

Developer of protein-degrading therapeutics designed to treat cancer and other serious diseases. Plexium is based in San Diego, CA and was founded in 2017. It was valued at $200 million at its later-stage round in Aug 2025, the last priced event on record. It has raised $225 million across 2 recorded rounds; the latest was a $60.1 million later-stage round in Jul 2025.

PMV mark · valuation
$200.0M
Oct 2026
Priced at
its later-stage round
Aug 2025
Total raised
$225.1M
Last round
Later Stage VC
Jul 2025

Plexium key facts

as of Oct 2026
  • Developer of protein-degrading therapeutics designed to treat cancer and other serious diseases.
  • Plexium is valued at approximately $200.0M as of Oct 2026, set at its later-stage round, Aug 2025; nothing has traded since, per PrivateMarketView’s mark.
  • It has raised $225.1M across 2 recorded rounds; the latest was Later Stage VC ($60.1M) in Jul 2025.
  • Notable investors include RA Capital Management, New Enterprise Associates, SoftBank Investment Advisers, Lux Capital, University of California — 18 tracked in total.
  • Plexium has filed 1 Form D with the SEC, most recently Aug 2025 ($60.1M sold to 20 investors).
  • Status: Privately Held (backing).
PrivateMarketView mark
LOW confidence
$200.0M

Valued at $200.0M at its later-stage round, Aug 2025. Nothing has traded since.

set by its last priced roundas of Oct 2026question about this number?
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Plexium funding rounds

2 rounds
Jul 2025Later Stage VC$60.1MSEC filing▮
Feb 2022Later Stage VC (Series B)$102.0M▮
Full funding history →

Plexium valuation

Plexium was valued at $200 million at its later-stage round in Aug 2025. That is the last priced event on record: no secondary trade or institutional fund mark has moved the figure since.

How much has Plexium raised?

Plexium has raised $225 million in total; 2 of its rounds are on record. The largest on record was a $60.1 million later-stage round in Jul 2025.

Plexium has filed 1 Form D with the SEC, most recently in Aug 2025 ($60.1 million sold to 20 investors).

Plexium investors

18 investors are on record for Plexium, including RA Capital Management, New Enterprise Associates, SoftBank Investment Advisers and Lux Capital. By type, the record holds 6 venture capital firms, 1 hedge fund and 1 asset manager. The later-stage round in Jul 2025 drew 20 investors.

Comparable companies

Comparable drug discovery names by valuation on PrivateMarketView: Adcytherix ($213 million), Adcendo ($210 million) and Ajax Therapeutics ($193 million).

About Plexium

Developer of protein-degrading therapeutics designed to treat cancer and other serious diseases. The company identifies novel small molecules that redirect ligases to targets of interest or induce degradation of targets by directly binding to them, enabling the medical community to combat cancer and inflammatory diseases in an improved manner.

Industry
Drug Discovery
Sector
Healthcare
HQ
San Diego, CA, United States
Founded
2017
Employees
52
Ownership
Privately Held (backing)

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