Nocion Therapeutics

Drug Discovery · Watertown, MA · Founded 2017 · Privately Held (backing)

Developer of a small molecule charged sodium channel designed to treat the conditions arising from neurogenic inflammation. Nocion Therapeutics is based in Watertown, MA and was founded in 2017. Its last reported valuation was $112 million in Aug 2021. It has raised $153 million across 3 recorded rounds; the latest was a $23 million early-stage round in Dec 2025.

Last reported valuation
$112.0M
Oct 2026
Priced at
—
Total raised
$153.0M
Last round
Early Stage VC
Dec 2025

Nocion Therapeutics key facts

as of Oct 2026
  • Developer of a small molecule charged sodium channel designed to treat the conditions arising from neurogenic inflammation.
  • Nocion Therapeutics is valued at approximately $112.0M as of Oct 2026 (last reported valuation).
  • It has raised $153.0M across 3 recorded rounds; the latest was Early Stage VC ($23.0M) in Dec 2025.
  • Notable investors include RA Capital Management, F-Prime Capital, Eight Roads, Alexandria Venture Investments, Canaan Partners — 16 tracked in total.
  • Nocion Therapeutics has filed 5 Form Ds with the SEC since 2021, most recently Mar 2026 ($23.0M sold to 13 investors).
  • Status: Privately Held (backing).
Last reported valuation
LOW confidence
$112.0M

Nocion Therapeutics's last reported valuation, Aug 2021. Nothing priced has surfaced since.

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Nocion Therapeutics funding rounds

3 rounds
Dec 2025Early Stage VC$23.0MSEC filing▮
Feb 2024Early Stage VC$31.1MSEC filing▮
Aug 2021Early Stage VC (Series A2)$7.0M▮

Nocion Therapeutics valuation

Nocion Therapeutics's last reported valuation was $112 million in Aug 2021. No priced round, secondary trade or fund mark has surfaced since.

How much has Nocion Therapeutics raised?

Nocion Therapeutics has raised $153 million in total; 3 of its rounds are on record, from 2021 on. The largest on record was a $7 million Series A2 in Aug 2021; the most recent was a $23 million early-stage round in Dec 2025.

Nocion Therapeutics has filed 5 Form Ds with the SEC since 2021, most recently in Mar 2026 ($23 million sold to 13 investors).

Nocion Therapeutics investors

16 investors are on record for Nocion Therapeutics, including RA Capital Management, F-Prime Capital, Eight Roads and Alexandria Venture Investments. By type, the record holds 5 venture capital firms and 2 asset managers. The early-stage round in Dec 2025 drew 13 investors.

Comparable companies

Comparable drug discovery names by valuation on PrivateMarketView: Arsenal Medical ($124 million), Stylus Medicine ($114 million) and Kernalbio ($111 million).

About Nocion Therapeutics

Developer of a small molecule charged sodium channel designed to treat the conditions arising from neurogenic inflammation. The company creates notions that target activated sensory neurons and enter activated nociceptors via large-pore channels on these neurons, enabling patients to gain relief through the treatment of serious conditions, including cough, itch, pain, and inflammation.

Industry
Drug Discovery
Sector
Healthcare
HQ
Watertown, MA, United States
Founded
2017
Employees
17
Ownership
Privately Held (backing)

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