Comanche Biopharma

Concord, MA · Founded 2020 · Privately Held (backing)

Operator of a biopharmaceutical company intended to develop an investigational siRNA medicine for preterm preeclampsia. Comanche Biopharma is based in Concord, MA and was founded in 2020. It was valued at $210 million at its later-stage round in Oct 2025, the last priced event on record. It has raised $136 million across 2 recorded rounds; the latest was a $37.5 million early-stage round in Dec 2023.

PMV mark · valuation
$210.0M
Oct 2026
Priced at
its later-stage round
Oct 2025
Total raised
$136.1M
Last round
Early Stage VC
Dec 2023

Comanche Biopharma key facts

as of Oct 2026
  • Operator of a biopharmaceutical company intended to develop an investigational siRNA medicine for preterm preeclampsia.
  • Comanche Biopharma is valued at approximately $210.0M as of Oct 2026, set at its later-stage round, Oct 2025; nothing has traded since, per PrivateMarketView’s mark.
  • It has raised $136.1M across 2 recorded rounds; the latest was Early Stage VC ($37.5M) in Dec 2023.
  • Notable investors include GV, New Enterprise Associates, F-Prime Capital, Atlas Venture, Broadview Ventures — 8 tracked in total.
  • Comanche Biopharma has filed 2 Form Ds with the SEC since 2023, most recently Jan 2024 ($37.5M sold to 7 investors).
  • Status: Privately Held (backing).
PrivateMarketView mark
LOW confidence
$210.0M

Valued at $210.0M at its later-stage round, Oct 2025. Nothing has traded since.

set by its last priced roundas of Oct 2026question about this number?
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Comanche Biopharma funding rounds

2 rounds
Dec 2023Early Stage VC$37.5MSEC filing▮
Jun 2021Early Stage VC$36.1MSEC filing▮

Comanche Biopharma valuation

Comanche Biopharma was valued at $210 million at its later-stage round in Oct 2025. That is the last priced event on record: no secondary trade or institutional fund mark has moved the figure since.

How much has Comanche Biopharma raised?

Comanche Biopharma has raised $136 million in total; 2 of its rounds are on record. The largest on record was a $37.5 million early-stage round in Dec 2023.

Comanche Biopharma has filed 2 Form Ds with the SEC since 2023, most recently in Jan 2024 ($37.5 million sold to 7 investors).

Comanche Biopharma investors

8 investors are on record for Comanche Biopharma, including GV, New Enterprise Associates, F-Prime Capital and Atlas Venture. The early-stage round in Dec 2023 drew 7 investors.

About Comanche Biopharma

Operator of a biopharmaceutical company intended to develop an investigational siRNA medicine for preterm preeclampsia. The company provides access to evidence-based and affordable therapies for treating life-threatening complications of pregnancy, enabling women to avail themselves of cost-effective and sustainable preeclampsia treatment at its root cause.

Sector
Healthcare
HQ
Concord, MA, United States
Founded
2020
Employees
29
Ownership
Privately Held (backing)

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