Circle Pharma

South San Francisco, CA · Founded 2012 · Privately Held (backing)

Developer of a new generation of macrocycle therapies designed for cell-permeable delivery and can be delivered by multiple routes, including oral administration. Circle Pharma is based in South San Francisco, CA and was founded in 2012. It was valued at $269 million at its later-stage round in Jan 2025, the last priced event on record. It has raised $212 million across 4 recorded rounds; the latest was a $92.4 million later-stage round in Jun 2024.

PMV mark · valuation
$269.0M
Oct 2026
Priced at
its later-stage round
Jan 2025
Total raised
$212.1M
Last round
Later Stage VC
Jun 2024

Circle Pharma key facts

as of Oct 2026
  • Developer of a new generation of macrocycle therapies designed for cell-permeable delivery and can be delivered by multiple routes, including oral administration.
  • Circle Pharma is valued at approximately $269.0M as of Oct 2026, set at its later-stage round, Jan 2025; nothing has traded since, per PrivateMarketView’s mark.
  • It has raised $212.1M across 4 recorded rounds; the latest was Later Stage VC ($92.4M) in Jun 2024.
  • Notable investors include Hemisphere Ventures, CSC UpShot Ventures, Mission BioCapital, Pfizer Ventures, Euclidean Capital — 23 tracked in total.
  • Circle Pharma has filed 7 Form Ds with the SEC since 2016, most recently Jan 2025 ($92.4M sold to 14 investors).
  • Status: Privately Held (backing).
PrivateMarketView mark
LOW confidence
$269.0M

Valued at $269.0M at its later-stage round, Jan 2025. Nothing has traded since.

set by its last priced roundas of Oct 2026question about this number?
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Circle Pharma funding rounds

4 rounds
Jun 2024Later Stage VC$92.4MSEC filing▮
Jun 2021Later Stage VC$66.3MSEC filing▮
Mar 2020Early Stage VC$15.0MSEC filing▮
Sep 2016Seed Round$3.8MSEC filing▮

Circle Pharma valuation

Circle Pharma was valued at $269 million at its later-stage round in Jan 2025. That is the last priced event on record: no secondary trade or institutional fund mark has moved the figure since.

How much has Circle Pharma raised?

Circle Pharma has raised $212 million across 4 recorded rounds since 2016. The largest was a $92.4 million later-stage round in Jun 2024.

Circle Pharma has filed 7 Form Ds with the SEC since 2016, most recently in Jan 2025 ($92.4 million sold to 14 investors).

Circle Pharma investors

23 investors are on record for Circle Pharma, including Hemisphere Ventures, CSC UpShot Ventures, Mission BioCapital and Pfizer Ventures. By type, the record holds 5 venture capital firms and 1 family office. The later-stage round in Jun 2024 drew 14 investors.

About Circle Pharma

Developer of a new generation of macrocycle therapies designed for cell-permeable delivery and can be delivered by multiple routes, including oral administration. The company's platform combines structure-based rational drug design and advanced synthetic chemistry to develop first-in-class macrocycle therapeutics for challenging targets to address unmet clinical needs, enabling doctors to focus on internal development efforts on intracellular protein-protein interactions that are key drivers in cancer.

Sector
Healthcare
HQ
South San Francisco, CA, United States
Founded
2012
Employees
56
Ownership
Privately Held (backing)

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