Bluestem Biosciences

Omaha, NE · Founded 2022 · Privately Held (backing)

Developer of a digital biology platform designed to build biology for strategic opportunities around agriculture and infrastructure. Bluestem Biosciences is based in Omaha, NE and was founded in 2022. It was valued at $135 million at its seed round in Dec 2025, the last priced event on record. It has raised $21 million across 1 recorded round; the latest was a $5 million early-stage round in Jul 2022.

PMV mark · valuation
$135.0M
Oct 2026
Priced at
its seed round
Dec 2025
Total raised
$21.0M
Last round
Early Stage VC
Jul 2022

Bluestem Biosciences key facts

as of Oct 2026
  • Developer of a digital biology platform designed to build biology for strategic opportunities around agriculture and infrastructure.
  • Bluestem Biosciences is valued at approximately $135.0M as of Oct 2026, set at its seed round, Dec 2025; nothing has traded since, per PrivateMarketView’s mark.
  • It has raised $21.0M across 1 recorded rounds; the latest was Early Stage VC ($5.0M) in Jul 2022.
  • Notable investors include US National Science Foundation, U.S. Department of Energy, Invest Nebraska, Zero Infinity Partners, PGSA Venture Capital — 9 tracked in total.
  • Bluestem Biosciences has filed 1 Form D with the SEC, most recently Aug 2022 ($5.0M sold to 19 investors).
  • Status: Privately Held (backing).
PrivateMarketView mark
MEDIUM confidence
$135.0M

Valued at $135.0M at its seed round, Dec 2025. Nothing has traded since.

set by its last priced roundas of Oct 2026question about this number?
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Bluestem Biosciences funding rounds

1 rounds
Jul 2022Early Stage VC$5.0MSEC filing▮

Bluestem Biosciences valuation

Bluestem Biosciences was valued at $135 million at its seed round in Dec 2025. That is the last priced event on record: no secondary trade or institutional fund mark has moved the figure since.

How much has Bluestem Biosciences raised?

Bluestem Biosciences has raised $21 million in total; 1 of its rounds is on record. The largest on record was a $5 million early-stage round in Jul 2022.

Bluestem Biosciences has filed 1 Form D with the SEC, most recently in Aug 2022 ($5 million sold to 19 investors).

Bluestem Biosciences investors

9 investors are on record for Bluestem Biosciences, including US National Science Foundation, U.S. Department of Energy, Invest Nebraska and Zero Infinity Partners. The early-stage round in Jul 2022 drew 19 investors.

About Bluestem Biosciences

Developer of a digital biology platform designed to build biology for strategic opportunities around agriculture and infrastructure. The company's platform facilitates the discovery of biomanufacturing and focuses on the sustainable production of chemicals and materials through proprietary biology built for anaerobic fermentation conditions, enabling clients to use programmable biology for the manufacturing of commodity chemicals.

Sector
Materials and Resources
HQ
Omaha, NE, United States
Founded
2022
Employees
11
Ownership
Privately Held (backing)

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